Otu n'ime ọgwụ ndị na-edozi ọgwụ arrhythmia kachasị dị irè bụ Asparkam. Ihe kachasị mkpa nke ihe ọ na-eme bụ normalization nke metabolism na electrolytes. Ọ bụ metabolite, isi iyi nke potassium na magnesium. N'ihi nke a, ọ na - eme ka usoro obi dị mma. Ọgwụ a bụ nke otu ọnụahịa onye kwuo uche ya kachasị dị, mana nke a anaghị egbochi ya ịdị irè karịa ọtụtụ analogues dị oke ọnụ. Ndị na-eme egwuregwu na-ahụ asọmpi Asparks anya ka ha wee nwee ike tufuo paụnd ego ọzọ n’azụ oge ọchịchị mmanya na-aba ụba
Mejupụtara
Asparkam dị n'ụdị mbadamba na ihe ngwọta maka ịgba ntụtụ. Ihe ngwugwu a nwere mkpụrụ ọgwụ 50 ma ọ bụ ampoulu 10 nke 5, 10 ml.
- Mbadamba ọ bụla nwere 0,2 g nke potassium na magnesium, yana ndị excipients maka cachet.
- Ihe ngwọta nke Asparkam nwere anhydrous magnesium aspartate - 40 mg na potassium - 45 mg. Nke a yiri 3 mg nke ezigbo magnesium na 10 mg nke ezigbo potassium. Na mgbakwunye, ụdị injectation nwere sorbitol na mmiri.
Potassium na-enyefe nsogbu akwara, na-egosipụta ihe na-egbu mamịrị ma na-ekere òkè dị ukwuu na mkpịsị akwara. Magnesium bụ maka ọrụ enzymatic, na-ekere òkè na njem nke ion na uto sel.
Usoro nke ime ihe bu iji dozie usoro metabolism na potassium na magnesium. Ihe ndị a na-emeri akpụkpọ ahụ sel n'ụzọ dị mfe ma mejupụta ụkọ nke microelements furu efu n'okpuru mmetụta nke oge ma ọ bụ mgbanwe ngbanwe ahụ. Normdị nhazi nke electrolyte na-eduga na mbelata nke conductive nke myocardium, na-emenyụ ọkụ ya ma na-enye ohere ka ọkụ eletrik nke usoro mmezi obi na-arụ ọrụ na ọnọdụ a na-emebu.
N'otu oge ahụ, usoro metabolism na-emeziwanye, ike myocardium na glycosides nke obi na-aka mma, ebe ọ bụ na nsị ha na-ada nke ọma. Ngwongwo akwara na-azakwa na mgbanwe ndị na-eme, ebe ọ bụ na mkparịta ụka nkịtị nke obi na-enye ha ohere ịnye ezigbo ọbara maka akụkụ ahụ na anụ ahụ nwere nri na oxygen.
Ion ion magnesium na-arụ ọrụ ATP, nke na-eme ka usoro sodium na-aga n’ime oghere intercellular na potassium n’ime oghere intracellular. Mbelata nke ịta ahụhụ Na + n'ime sel na-egbochi mgbanwe nke calcium na sodium na akwara na-akwọ akwara, nke na-atụgharị ha na akpaghị aka. Uto nke K + na-akpali mmepụta nke ATP - isi iyi nke ike, glycogen, protein na acetylcholine, nke na-egbochi ischemia obi na hypoxia cellular.
Asparkam na-abanye n'ọbara site na tract digestive, site na ebe ahụ - n'ụdị aspartate n'ime myocardium, ebe ọ malitere ịrụ ọrụ iji meziwanye metabolism.
Njirimara
Ha bụ n'ihi mmetụta jikọtara potassium na magnesium na akwara obi ma nyere aka weghachi ya mgbe nkụchi obi gasịrị. K + na-eme ka nkwonkwo obi nwee ike belata site na mbenata oke ọkụ ma melite nrụpụta ahụ ike. Ọ na-agbasawanye lumen nke nnukwu arịa nke obi. Magnesium na - akpali njikọ nke amino acid dị mkpa iji mejupụta nkwarụ anụ ahụ ike ma na - akpali nkewa sel, na - eme ka ọ dịghachi ngwa ngwa.
A na-eji ihe ndị a eme ihe na ọgwụgwọ glaucoma na nnukwu intracranial pressure. Normalization nke metabolism na electrolyte itule belata fọrọ nke nta niile na-adịghị mma mgbaàmà metụtara na vaskụla bufee. Mmetụta dị n'akụkụ bụ uto ahụ ike ngwa ngwa, nke gosipụtara na ọ dị mkpa maka ndị na-eme egwuregwu. Ya mere, Asparkam ama ama na egwuregwu ike.
Potassium na magnesium
Cardiologists na-ekwu okwu oge niile banyere mkpa ihe ndị a achọpụtara. Enweghị ihe ijuanya na nke a. A na-ekpebi usoro nke mkpịsị obi site na ọrụ dị elu nke usoro myocardial, nke a na-eme mkpali na-enweghị onwe ya, na, na-agabiga ngwugwu nke eriri akwara pụrụ iche, ha na-eme ka ọnụọgụ nke atria na ventricles dị na usoro ụfọdụ. Omume nke eriri ndị a na-adabere na ịta nke magnesium na potassium n'ime ha.
Obi obim bu ihe di nma, nke putara na onye ahu enwekwara obi oma, ebe obu na akuku obula n’enweta nri kwesiri ekwesiri na ikuku oxygen n’oge na n’usoro doro anya. Na enweghị magnesium, nsogbu na-amalite na arịa akwara ọbara. Ha na-adị nro ma ghọọ obosara. N’ihi ya, ọbara na-eme ka ọ kwụsị ịgbasa, akụkụ ahụ ndị ahụ na-amalite inwe ahụ erughị ala, onye ọrịa ahụ amalitekwa ịka njọ.
A na - ahụ ihe megidere ya na ngaji nke potassium: akwara ọbara na - emebi ma wara wara. Ma nke a na-ewetakwa nsogbu ụfọdụ nrugharị ọbara, ebe ọ bụ na ọbara enweghị ike ịbanye n'okporo ụzọ awara awara na oke ya ma banye ya na akụkụ ahụ. Ọnwụ nke magnesium site na mkpụrụ ndụ, nhapụ ya n'ime oghere intercellular gụnyere mbibi nke carbohydrates dị mgbagwoju anya, a na-eme hyperkalemia.
Magnesium na-ekere òkè na usoro metabolic niile na-enweghị isịneke. Ọ bụ ihe na-akpali akpali maka nkewa sel, njikọ RNA, ma na-enye akara edokọbara maka ozi sitere na mmadụ. Ma ọ bụrụ na njupụta ya na-ebelata, mkpụrụ ndụ sel na - aghọ ihe mgbochi a na - apụghị imeri emeri maka ihe ahụ achọpụtara. Asparks magnesium na-enyere aka ịbanye na ya na mgbakwunye ego nke mmewere.
Enwere ọnyà dị ebe a. Doụbiga ọgwụ ókè na hypermagnesemia jupụtara na ya, nke a bụ ihe kpatara obi njide. Ya mere, anabataghi ndenye ọgwụ nke "adịghị njọ".
Nchịkọta nke potassium na magnesium na cell dị ezigbo mkpa n'oge ime ime. Ha na eme ka nwa ebu n’afọ na-eto eto. Mana edere Asparkam nye ndị inyom dị ime na nlekọta dị ukwuu, na-ahọrọ German Panangin - vitamin maka obi. Nnukwu mgbaàmà gụnyere ike ọgwụgwụ na dysuria.
Nuance ọzọ: enweghi potassium na-agbanwe mgbanwụ ụjọ, yana ụkọ nke magnesium intracellular na - ebute enweghị nnabata na ọgbọ na oriri ike, nke na - akpali mkpọnwụ, nhịahụ nke aka na aka, na ike ọgwụgwụ.
Egosi maka iwere Asparkam
Isi ọrụ nke Asparkam bụ ibugharị ihe dị n’ime cell. Ọgwụ ọgwụ na-esonụ ikpe:
- Enweghi ike nke K + na Mg + n'ime ahụ.
- Nsogbu obi.
- Ọrịa obi Ischemic, ọnọdụ postinfarction.
- Extrasystole nke ventricles.
- Foxglove ekweghị ibe nọrọ.
- Ujo ala.
- Nsogbu ọbara na-adịghị ala ala.
- Atrial fibrillation.
- Obi mgbawa.
- Site na ọnwa anọ ka akwadoro ya na Diacarb iji dozie nrụgide intracranial. A na-eji nchikota a iji gwọ glaucoma, epilepsy, edema, gout.
Egwuregwu
Nke a apụtaghị na Asparkam nwere mmetụta dị mkpa na uru uru. Ya mere, na tiori, maka egwuregwu ọ bụghị ọgwụ ịhọrọ. Mana, ka o sina dị, ọ na-ewu ewu n'etiti ndị egwuregwu. Nkọwa dị mfe: mgbe ha na-enwetakwu pound, ndị na-eme egwuregwu na-eri ọtụtụ calorie n'ụdị protein, carbohydrates, na abụba. N'otu oge ahụ, ihe ndị na-achọpụta dị obere obere nri. O doro anya na ezughị ezu maka arụmọrụ obi. Ọzọkwa, enweghi potassium na magnesium na-eduga n'ọgwụ ike dị elu n'ihi nrụrụ metabolic. Asparks na nke a bụ ihe na-apụghị ịgbanwe agbanwe.
Kọmpat, dị mfe iji ma jupụta na mkpa K + na Mg +:
- Na-ebelata ike ọgwụgwụ.
- Nkwụghachi ụgwọ maka erughị eru micronutrient.
- Na-ebelata adịghị ike akwara.
- Na-eme ka ọrụ myocardium kwụsie ike.
- Na-akpali ntachi obi.
- Na-egbochi AMI na ONMK.
Idozi ahu
N'ihe banyere ozuzu, ebe a Asparkam na-arụ ọrụ dị ka ezigbo metabolite. Ọ bụ na ọzụzụ ọzụzụ ike na mmetụta dị n'akụkụ ya nke ụlọ ahụ ike na-achọ. Potassium nwere mmetụta dị mma na ọsọ nke mmeghachi omume nke metabolic, magnesium na-etinye aka na metabolism metabolism. N'okwu a, uto nke sel na-enweghi mkpokọta abụba na njigide mmiri n'ime ahụ. Nke a bụ isi okwu dị oke mkpa, ebe ọ bụ na n'oge ọzụzụ, ndị na-eme egwuregwu na-a aụ nnukwu mmiri, nke na-asacha ihe ndị na-achọpụta. Nke a pụtara na mmụgharị ha mejupụtara chọrọ mkpa ngwa ngwa.
Iwetulata ibu
Ezi uche nke ị takingụ ọgwụ ahụ dabere na otu ihe ama ama ama nke magnesium na potassium. Mg + dị mkpa site na sistem ụjọ nke etiti, na K + na-enyere akwara niile dị na ahụ aka. Ha niile na-agbazi nguzo mmiri na nnu, wepu ọzịza. N'ihi atụmatụ a, a na-eji Asparkam eme ihe maka ọnwụ: iwepu mmiri si n'ahụ na-enye gị ohere ifelata. N'otu oge ahụ, oke abụba anụ ahụ adịghị agbanwe agbanwe, n'ihi ya, ọ dịbeghị nkewa ọgwụ a dịka ụzọ isi nyere aka ịkwụsị ibu. Inweta ya n'echeghị echiche dị ize ndụ, n'ihi na ọ bụ metabolite, na metabolism bụ ihe aghụghọ dị nro. Excessmebiga ihe dị iche iche na-agụnye nsonaazụ na-adịghị mma, mana ọ dịghị ụzọ na-eme ka usoro metabolism dị ngwa.
Contraindications na usoro nlekọta
Enwere ole na ole contraindications, mana ha dị mkpa:
- Onye ekweghị ibe nọrọ ma ọ bụ mmetụta nke ahụ.
- Dysfunction nke adrenal glands na akụrụ.
- Myosthenia.
- Cardiogenic ujo.
- Ogwe mkpọchi 2-3.
- Metabolic acidosis.
- ARF na ọdịda akụrụ na-adịghị ala ala, anuria.
- Hemolysis.
- Akpịrị ịkpọ nkụ.
- Afọ n'okpuru 18.
Achọpụtaghị mmetụta nke Asparkam n'ahụ ahụ n'ụzọ zuru ezu. N'ihi nke a, a na-eji ya akpachara anya n'oge afọ ime ma edeghị ya maka ụmụaka. Ndị agadi na-arịa ọrịa nọkwa n'ihe ize ndụ, ebe ọ bụ na metabolism ha na-ebelata ihe kachasị mkpa n'ihi mgbanwe ndị metụtara afọ. Agbanyeghị, na ọrịa nke sistemu obi, ana anabata onye ọrụ maka nnabata na-enweghị mgbochi. Wayzọ a na-emebu iji were mbadamba ụrọ ugboro atọ n'ụbọchị mgbe nri.
Mmetụta dị n'akụkụ
Asparkam nwere ọ bụghị naanị mmetụta dị mma, kamakwa nke na-adịghị mma. A na-ahụ ha site na mgbaàmà ndị a:
Mmetụta nke adịghị ike, adịghị ike, nju anya.
- Ike adịghị ike.
- Akpụkpọ anụ ahụ.
- Ọgbụgbọ.
- Dyspepsia.
- Akọrọ ọnụ.
- Ikupu
- Ọbara n'ike.
- Hyperhidrosis.
- Dyspnea.
- Akwara thrombosis.
Na mgbakwunye, ịdoụbiga mmanya ókè ga-ekwe omume, nke gosipụtara onwe ya:
- hyperkalemia;
- hypermagnesemia;
- acha uhie uhie;
- akpịrị ịkpọ nkụ;
- arrhythmia;
- mkpụkpu;
- hypotension nke akwara;
- mgbochi obi;
- mmegbu nke etiti iku ume na ụbụrụ.
Mgbaàmà ndị a chọrọ ndụmọdụ ahụike. Na mkpokọta, iji Asparkam mee ogologo oge chọrọ nlekota ọkwa electrolyte, ebe ọ bụ:
- enwebeghị nchekwa zuru oke nke ọgwụ ahụ;
- mgbe ejikọtara ya na tetracyclines, iron na fluorine, ọgwụ ahụ na-egbochi mmetụ ha (oge ga-adị n'etiti ọgwụ ga-adịkarịa ala elekere atọ);
- enwere ihe egwu nke ibute hyperkalemia.
Ndakọrịta
Ọ nwere iche iche. Site na echiche nke pharmacodynamics, nchikota na diuretics, beta-blockers, cyclosporins, NSAIDs, heparin na-akpali mmepe nke asystole na arrhythmia. Nchikota na homonụ na-akwụsị ọnọdụ a. Ion ion potassium na-ebelata mmetụta ọjọọ nke cardiac glycosides. Ion Magnesium - neomycin, streptomycin, polymyxin. Calcium na-ebelata ọrụ nke magnesium, yabụ ịkwesịrị ijikọta ego ndị dị otú ahụ na nnukwu nlekọta, maka ahụike.
Pharmacokinetics dọrọ aka ná ntị banyere enweghị ike Asparkam na astringent na mkpuchi ọgwụ, ebe ọ bụ na ha na-ebelata absorption nke ọgwụ na tube nri ma na-atụ aro, ọ bụrụ na ọ dị mkpa, na-edebe oge elekere atọ n'etiti usoro.
Tụnyere Panangin
A na-ahụkwa Potassium na magnesium na ọgwụ ọzọ na-ewu ewu. Anyị na-ekwu maka Panangin. A na-egosipụta njirimara na-atụnyere ọgwụ ọgwụ na tebụl.
Akụrụngwa | Mbadamba | Ngwọta | ||
Panangin | Asparkam | Panangin | Asparkam | |
Potassium na-arụ ọrụ | 160 mg | 180 mg | 45 mg / ml | |
Aspartate nke magnesium | 140 mg | 10 mg / ml | ||
Ntughari ka ion ion | 36 mg | |||
Ntughari na Mg + ion | 12 mg | 3.5 mg / ml | ||
Enyemaka | Silica, povidone, talc, magnesium stearate, stachi, macrogol, nnu titanium, metcric acid copolymers. | Starch, talc, calcium stearate, n'etiti-80. | Ọgwụ mmiri. | Mmiri maka ogwu ogbugba, sorbitol. |
O doro anya na ihe ndị na-arụ ọrụ na ọgwụ abụọ ahụ bụ otu, ọdịiche dị na cachet, nke na-adịghị emetụta ọgwụ ọgwụ nke ọgwụ. Otú ọ dị, Panangin nwere akpụkpọ ahụ ihe nkiri nke na-echebe mucosa mucosa na ezé site na ọgwụ na-egbu egbu nke onye ọrụ ahụ. Ya mere, onye ọ bụla nwere nsogbu na usoro nsị na-atụ aro Panangin, ọnụahịa ya dị elu karịa ọnụ Asparkam ọtụtụ ugboro.