Acetyl-carnitine (Acetyl-L-carnitine ma ọ bụ ALCAR maka mkpụmkpụ) bụ ụdị ester nke amino acid L-carnitine nke otu acetyl dị na ya. Ndị na-emepụta ihe mgbakwunye egwuregwu nwere ALCAR na-ekwu na ụdị L-carnitine a dị irè karị maka iji ya mee egwuregwu, ebe ọ nwere bioavailability dị elu, ya mere enwere ike iji ya rụọ ọrụ na otu mmetụta. Agbanyeghị, ekwesiri iburu n'uche na ekwenyebeghị esemokwu a.
Akụkụ nke ụdị acetyl, ọdịiche dị n'etiti L-carnitine na acetylcarnitine
Acetylcarnitine na L-carnitine bụ ụdị abụọ dị iche iche nke otu ogige ahụ nwere ụdị kemịkalụ ndị ahụ mana ha dị iche na njirimara.
L-carnitine
L-carnitine (levocarnitine) bụ amino acid, ngwakọta metụtara vitamin B, ọ bụkwa otu n'ime isi njikọ na metabolism nke abụba na sel. Ihe a na-abanye n'ime ahụ mmadụ na nri (anụ, mmiri ara ehi na ngwaahịa mmiri ara ehi, anụ ọkụkọ), ma na-arụkọkwa n'ime imeju na akụrụ, site na ebe a na-ekesa ya na anụ ahụ na akụkụ ndị ọzọ.
Fọdụ usoro ihe ndị dị mkpa dị na ahụ nwere ike ghara ịga n'ihu na-enweghị L-carnitine. Enweghị ihe a nwere ike ịbụ n'ihi ihe nketa ma ọ bụ ọnọdụ nchịkwa, dịka ọmụmaatụ, ọrịa akụrụ na-adịghị ala ala. Nakwa, nbelata na njikọ nke L-carnitine nwere ike ịkpasu oriri nke ụfọdụ ọgwụ, dịka ọmụmaatụ, meldonium.
Na enweghi carnitine n'ime ahụ, ndị dọkịta na-ede ọgwụ ndị na-eweghachite ma jigide ọdịnaya ya na anụ ahụ. Maka ebumnuche ọgwụgwọ, a na-eji ndị ọrụ L-carnitine agwọ ọrịa nke obi na arịa ọbara, ụdị ụfọdụ nke muscular dystrophy na-aga n'ihu, thyrotoxicosis, oge uto na ụmụaka, akpụkpọ na ọtụtụ ọrịa ndị ọzọ.
Ndị na-arụsi ọrụ ike na egwuregwu na-ewere L-carnitine. A na-eji ihe oriri na-edozi ahụ nke nwere amino acid mee ihe dị ka ome osooso nke usoro metabolic.
Site na mmega ahụ siri ike, L-carnitine na-enyere aka ịgbanwe asịrị abụba n'ime ume, yabụ a na-atụ aro ka iwere ya iji mee ka ọnwụ dị ngwa na abụba dị ọkụ. Nnukwu ntọhapụ nke ike na-enyere aka ịbawanye arụmọrụ nke ọzụzụ site na ịbawanye ntachi obi.
Na mbụ echere na L-carnitine na-arụ ọrụ anabolic, mana echiche a ekwenyela. Ka o sina dị, ihe mgbakwunye na ihe a na-anọgide na-ewu ewu na egwuregwu. Mgbe ejiri ya na steroid, a na-emewanye mmetụta nke L-carnitine.
Acetylcarnitine
Acetylcarnitine bụ ụdị ester nke L-carnitine nke etinyere otu acetyl. N'adịghị ka ụdị amino acid ndị ọzọ, ọ nwere ike ịgafe ihe nzacha nke ụbụrụ a na-akpọ mgbochi ụbụrụ ọbara.
Ndị na-emepụta mgbakwunye na-arụkarị ụka na acetylcarnitine bụ ụdị L-carnitine dị ọhụrụ na nke "dị elu", onye na-elekọta egwuregwu ogologo oge, si otú a na-agba ndị mmadụ ume ịzụta ngwaahịa ha. Otú ọ dị, n'eziokwu, mgbe ị na-eji otu ihe ahụ, ihe nke acetyl na-etinye n'ọbara dị ala, ya bụ, bioavailability dị ala karịa nke ụdị dị mfe nke levocarnitine. Ya mere, ikwesighi ịtụkwasị obi na nkwa nke ndị ahịa.
Ọ bụrụ na ebumnuche mmadụ bụ ifelata, mezie oke abụba na ahụ, mgbe ahụ, mgbakwunye na L-carnitine n'ụdị mbụ ma ọ bụ n'ụdị tartrate ka mma. Ma ikike nke ụdị acetyl iji merie mgbochi ụbụrụ ọbara na-ejikarị ya na ọgwụ maka ebumnuche ọgwụgwọ na prophylactic.
Acetylcarnitine na-abanye n'ime anụ ahụ nke sistem ụjọ, nke na-eme ka ọkwa carnitine dị n'ụbụrụ na-abawanye. Njirimara ndị a nke acetylcarnitine na-eme ka o kwe omume iji ọgwụ ọjọọ eme ihe dabere na ya n'ịgwọ ọrịa na ọnọdụ ndị a:
- Ọrịa Alzheimer;
- mgbaka cerebrovascular;
- mkpụrụ ndụ neuropathies, n’agbanyeghi ebe o sitere;
- encephalopathy vaskụla na syndromes na-enweghị mgbatị na-etolite na nzụlite ha;
- mmebi nke ọrụ ụbụrụ nke ụbụrụ, gụnyere mgbanwe mgbanwe metụtara afọ, yana mbelata nke ụbụrụ na-arụ ọrụ megide ndabere nke ịxicụbiga mmanya ókè ruo ogologo oge (dịka ọmụmaatụ, mmanya na-aba n'anya);
- ike ọgwụgwụ nke ọgụgụ isi;
- enweghi uche na umuaka.
A na-eji Acetylcarnitine eme ihe dị ka neuroprotector, ọgwụ neurotrophic, nwere mmetụta cholinomimetic, ebe ọ bụ na usoro ya yiri neurotransmitter acetylcholine.
A na-atụ aro ya iji meziwanye ụbụrụ ụbụrụ, na-eme ka nchịkwa nke eriri akwara.
Ofkpụrụ nke ngwa
Ndị nrụpụta dị iche iche na-akwado usoro dị iche iche na usoro nchịkwa. Ọtụtụ mgbe, a na-adụ ndị mgbakwunye egwuregwu na acetylcarnitine ka ha were tupu ma ọ bụ n'oge nri, yana 1-2 awa tupu ọzụzụ. Ọgwụ ndị dabere na onyinye a na-a drunkụbiga mmanya ókè n'agbanyeghị nri.
Enweghi ike ịchọta carnitine kwa ụbọchị n'ihi na ọ bụghị nri dị mkpa.
A na-ewere usoro ọgwụgwọ dị mma dị ka 500-1,000 mg nke ezigbo acetylcarnitine kwa dose. Ọ dị na capsules na ntụ ntụ maka reconstitution na mmiri.
Mgbe ị na-eji ọgwụ ọjọọ eme ihe na mgbakwunye na acetylcarnitine, a naghị ahụkarị mmetụta dị n'akụkụ. Mgbe ụfọdụ, ọgbụgbọ, obi mgbu, nsogbu nri, isi ọwụwa ga-ekwe omume, mana, dịka iwu, mmeghachi omume dị otú ahụ metụtara iji ego eme ihe na-ezighị ezi, mgbanwe na-enweghị isi na usoro onunu.
Mgbochi ịbata bụ ime ime, inye nwa ara, ekweghị ibe nọrọ mmadụ.
Jide n'aka na ị gakwuru dọkịta tupu ị drugsụ ọgwụ na acetylcarnitine maka ndị na-arịa ọrịa ndị a:
- gbasara akụrụ, imeju umeji;
- Akwụkwụ na-adọ;
- ọrịa nke obi, akwara ọbara;
- imebi ogo nke ọbara mgbali (ma na-abawanye ma na-ebelata);
- ọrịa cirrhosis;
- ọrịa shuga;
- nsogbu ihi ụra;
- nsogbu iku ume.
Acetylcarnitine bụ hydrolyzed na ọbara, nke nwere ike na-egosi ya ala ndu ọrụ. Uru nke ihe a na egwuregwu karịa ụdị L-carnitine dị na mbụ bụ ihe a na-enyo enyo, ọnụ ahịa ihe mgbakwunye na ya dịkwa elu.
Ikekwe ọ baghị uru ịzụta ihe mgbakwunye nri dị oke ọnụ karịa na acetylcarnitine. N'aka nke ọzọ, ihe a na - eme ka mmepụta ume ike n'oge mmega ahụ, na - enwekwa uru bara uru na ụbụrụ.
