Tyrosine - ọrụ dị na ahụ na uru bara uru nke amino acid

Tyrosine bụ aminocarboxylic acid dị mkpa na-emetụta na catabolism na anabolism, gụnyere njikọ nke protein protein, dopamine, na ndị na-ahụ maka ntanetị. Ejiri site na phenylalanine.

Usoro njikọ nke Tyrosine

Usoro ihe omuma nke tyrosine bu C₉H₁₁NO₃, phenylalanine bu C₉H₁₁NO₂. Emebere Tyrosine dị ka atụmatụ ndị a:

C₉H₁₁NO₂ + phenylalanine-4-hydroxylase => C₉H₁₁NO₃.

Ihe ndu mmadu nke tyrosine

Otu tyrosine n’aru aru na oru ya n’eme:

• na-eje ozi dị ka ihe rọba maka nhazi melanin, homonụ catecholamine ma ọ bụ catecholamines (adrenaline na norepinephrine, dopamine, thyroxine, triiodothyronine, L-dioxyphenalalanine), ndị na-ahụ maka ntanetị na ndị na-ahụ maka ntanetị;
• na-ekere òkè na ịrụ ọrụ nke thyroid na adrenal glands;
• amalite ntachi obi n'okpuru nrụgide, na-akwalite mgbake n'oge;
• nwere mmetụta dị mma na ịrụ ọrụ nke usoro ụjọ ahụ na ngwa vestibular;
• ihu ọma detoxification;
• na-egosipụta ihe mgbochi antidepressant;
• enwekwu uche uche;
• na-ekere òkè na mgbanwe okpomọkụ;
• na-egbochi catabolism;
• na-egbochi ihe ịrịba ama nke ọrịa premenstrual.

Ojiji nke tyrosine maka ụkọ ọnwụ

N'ihi ikike ya iji mee ka abụba dịkwuo mma, a na-eji L-tyrosine mee ihe n'oge akọrọ (ọnwụ ọnwụ) n'okpuru nlekọta nke dọkịta egwuregwu.

Ego ole tyrosine dị mkpa kwa ụbọchị

Dosebọchị nke tyrosine kwa ụbọchị sitere na 0.5-1.5 gram, dabere na ọnọdụ mmụọ na ọnọdụ mmụọ. A naghị atụ aro ka ewere amino acid maka ihe karịrị ọnwa 3. Ọ kachasị mma iri nri na obere mmiri.

Iji mee ka usoro ọgwụgwọ ahụ dịkwuo elu, a na-atụ aro tyrosine ka ejiri ya na methionine na vitamin B6, B1 na C.

Enweghị na ngafe nke tyrosine, ihe ịrịba ama na nsonaazụ

Njuju (hypertyrosinosis ma ọ bụ hypertyrosinia) ma ọ bụ ụkọ (hypothyrosinia ma ọ bụ hypothyrosinosis) nke amino acid tyrosine na ahụ nwere ike ibute nsogbu nke metabolic.

Mgbaàmà nke oke na enweghị tyrosine abụghị nke a kapịrị ọnụ, nke na-eme ka nchoputa siri ike. Mgbe ị na-eme nchoputa, ọ dị mkpa iburu n'uche ihe ọmụma anamnestic (ebufe n'ehihie nke ọrịa ahụ, ị ​​takenụ ọgwụ, ịnọ na nri).

Ngafe

Oké tyrosine nwere ike igosipụta onwe ya dị ka enweghị aha ọrụ:

• adrenal glands;
• usoro ụjọ na etiti;
• thyroid gland (hypothyroidism).

Ọghọm

A na-ahụ ụkọ amino acid na mgbaàmà ndị a:

• arụ ọrụ na ụmụaka;
• na-agbada ọbara mgbali elu (ọbara mgbali elu);
• mbelata nke okpomọkụ ahụ;
• igbochi mmega ahụ na nke uche n’ime ndị okenye;
• adịghị ike muscle;
• ịda mba;
• mgbanwe ọnọdụ uche;
• erite uru na nri oge niile;
• ọrịa ụkwụ na-enweghị ike;
• ntutu;
• ụra na-ehi ụra;
• agụụ na-ebelata.

Enweghi ike zuru oke nke tyrosine nwere ike ịbụ n'ihi enweghị nri ya na nri ma ọ bụ ezughị ezu site na phenylalanine.

A na-eji Hypertyrosinosis enwe akụkụ site na mmụba nke mmepụta nke thyroxine (ọrịa Graves):

• nhụsianya a na-ahụ anya na arọ ahụ;
• nsogbu ụra;
• ụba excitability;
• Ntughari;
• isi ọwụwa;
• tachycardia;
• mgbaàmà dyspeptic (enweghị agụụ, ọgbụgbọ, obi ilu, ịgba agbọ, ụba acidity nke ihe ọ juiceụ gastụ gastric, gastritis hyperacid ma ọ bụ gastric ma ọ bụ duodenal ulcer).

Nkwekọrịta

A naghị akwado nkwadebe Tyrosine maka iji:

• anabataghị anabata ma ọ bụ nfụkasị mmeghachi omume nke mmiri nke emeju ma ọ bụ ọgwụ;
• ọrịa nke thyroid gland (hyperthyroidism);
• ọrịa uche (schizophrenia);
• ihe nketa tyrosinemia;
• ọgwụgwọ na ndị na-emechi MAO (monoamine oxidase);
• Ọrịa Parkinson.

Mmetụta dị n'akụkụ

Mmetụta dị iche iche dị iche iche ma kpebisie ike ọ bụghị naanị site na njirimara onye ọ bụla nke mmadụ, kamakwa site n'ọtụtụ dịgasị iche iche nke mmeghachi omume nke mmiri ọgwụ nke aminocarboxylic acid. Na nke a, iji gbochie ha, a na-atụ aro ịmalite amino acid na usoro onunu kacha nta n'okpuru nlekọta nke dọkịta na-aga.

Mmetụta ndị kachasị emetụta gụnyere ọrịa ogbu na nkwonkwo, isi ọwụwa, obi mgbawa, na ọgbụgbọ.

Mmekọrịta

A naghị ewepụ mgbanwe nke ọgwụ ọgwụ nke tyrosine mgbe ejiri ya na mmanya, opiates, steroid ma ọ bụ mgbakwunye egwuregwu. Na nke a, ọ dị mma ịbawanye ọnụ ọgụgụ ọgwụ ndị eji nwayọ nwayọ iji wepu ihe na-adịghị mma ma ọ bụrụ na ọ dị mkpa.

Ihe oriri na-eri nri nke Tyrosine

A hụrụ amino acid na anụ nke mammals, nnụnụ na azụ, soybeans, ahụekere, ngwaahịa mmiri ara ehi, agwa, ọka wit, oatmeal, nri mmiri, nri nri.

Nri egwuregwu na L-tyrosine

L-Tyrosine dị na mbadamba 1100 mg na 400 mg, 500 mg ma ọ bụ 600 mg capsules. 1 plastic ite nwere mbadamba 60, ma ọ bụ 50, 60 ma ọ bụ 100 capsules. A na-eji microcrystalline cellulose, aerosil na Mg stearate eme ihe.

Ọnụahịa dị n'ụlọ ọgwụ maka capsules 60 nke 500 mg dị na 900-1300 rubles.

Ngwa na usoro

Ihe achọrọ kwa ụbọchị maka tyrosine maka onye toro eto bụ 25 mg / kg (1.75 g / day). Ihe eji eme ihe nwere ike ịdị iche na-adabere na ebumnuche nke iji ihe ahụ (dọkịta na-abịa abịa).

A na-atụ aro ka itughari ngwaahịa na tyrosine na apụl ma ọ bụ ihe ọ orangeụ orangeụ oroma.

Lelee vidiyo ahụ: Introduction to Shikimic Acid Pathway Part 01 = HINDI By Solution Pharmacy (Ka 2025).